synthetic

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Advancing synthetic Ephedra-type alkaloids with a two-step enzymatic approach

Identification of BsAlsS as an effective carboligase for the synthesis of PAC-class α-hydroxyketones. Credit: BioDesign Research (2024). DOI: 10.34133/bdr.0048 Ephedra-type alkaloids, a class of naturally occurring compounds derived from plants in the genus Ephedra, have long held interest in the pharmaceutical industry due to their stimulant and airway widening effects. These alkaloids are used for

The promise of synthetic cells

NIST researcher Elizabeth Strychalski’s research group is helping to establish the measurements and standards needed for progress in engineering biology, also known as synthetic biology. Credit: J. Stoughton/NIST For over a decade, scientists have made extraordinary progress on the long-held dream of fabricating an entire cell from nonliving molecules and materials. Such synthetic (or “engineered”)

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