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Pharmacists propose ways to increase the activity of levofloxacin and overcome bacterial resistance

3D chemical structure depiction of levofloxacin hemihydrate. Credit: Scientia Pharmaceutica (2023). DOI: 10.3390/scipharm92010001 The antibacterial drug levofloxacin is used to treat pneumonia, sinusitis, genitourinary infections, and other diseases. It is included in the WHO Model List of Essential Medicines. In terms of its chemical structure, it is a third-generation fluoroquinolone—a completely synthetic substance of the

Researchers propose post-synthetic modification of covalent organic frameworks for carbon dioxide electroreduction

Schematic illustration of multilevel post-synthetic modification. a Effects of reduction reaction, Menshutkin reaction and multilevel post-synthetic modification on the bond change and charge state. b The synthesis of N+-COF, NH-COF and N+-NH-COF from the base COF (CoTAPP-PATA-COF). Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-39544-9 Covalent organic frameworks (COFs), possessing ordered pores and high-precision functionalization, are regarded

Scientists propose novel method to estimate human-caused heat emission

Graphical abstract. Credit: Remote Sensing of Environment (2023). DOI: 10.1016/j.rse.2023.113602 Why are cities usually warmer than rural areas? Scientist have long known that cities retain heat more than rural areas, a phenomenon known as urban heat island (UHI), which is largely due to the impact of anthropogenic heating, or human-caused heating. A research team led

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