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Rational design of mRNA nanovaccine for cancer immunotherapy

(a) Anionic Lipo-ORG enabled effective access to lymphatics and high accumulation in lymph nodes. Effective cellular entry and endosome escape of mRNA and cGAMP was achieved in DCs and potentiated antigen presentation to T cells. Tumor antigens were presented after the release of mRNA. cGAMP activated STING pathway to trigger IFN-I, which amplified the innate

Tama Mischke October 17, 2023

Researchers design efficient iridium catalyst for hydrogen generation

Researchers from Korea and USA develop a novel iridium catalyst with enhanced oxygen evolution reaction activity, facilitating a cost-effective proton exchange membrane water electrolysis for hydrogen production. Credit: Chanho Pak from Gwangju Institute of Science and Technology The energy demands of the world are ever increasing. In our quest for clean and eco-friendly energy solutions

Margherita Culton August 16, 2023

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