A mechanism that controls the genomic structure during early differentiation into neuroectoderm
Fig. 1. Schematic presentation of how normal undifferentiated cells and Phc1 (Rae28)-deficient undifferentiated cells respond to neural inducers. Credit: Nara Institute of Science and Technology A group of scientists have discovered that a one of the components of the polycomb-type of transcriptional repressor complex (PRC), Phc1 (Rae28), regulates the chromatin state of cells and plays