Hexbyte Glen Cove Modulating cells' chloride channels thumbnail

Hexbyte Glen Cove Modulating cells’ chloride channels

TMEM16A(ac) S673A (gray) versus S673D (sky blue). The S673A mutant is the nonphosphorylatable form. The S673D mutant mimics phosphorylation of the serine residue. Credit: DGIST Laboratory cell experiments and computer simulations have revealed molecular mechanisms regulating a protein channel responsible for transporting chloride and other charged molecules across cell membranes. The findings were published...

Hexbyte Glen Cove Amino acid recycling in cells: Autophagy helps cells adapt to changing conditions thumbnail

Hexbyte Glen Cove Amino acid recycling in cells: Autophagy helps cells adapt to changing conditions

Autophagy-derived serine feeds into mitochondrial one-carbon metabolism,supporting the initiation of mitochondrial protein synthesis and allowing rapid adaptation torespiratory growth. Credit: Tokyo Tech Cells must utilize nutrient resources as efficiently as possible in order to ensure survival. This involves an intricate balance between the synthesis and degradation of cellular components, the latter of which can...

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