Generation of a human haploid neural stem cell line for genome-wide genetic screening
Characterization of the pluripotency and haploidy of extended pluripotent human haploid embryonic stem cells. Credit: World Journal of Stem Cells (2023). DOI: 10.4252/wjsc.v15.i7.734 Haploid embryonic stem cells (haESCs) have been established in many species. Differentiated haploid cell line types in mammals are lacking due to spontaneous diploidization during differentiation that compromises lineage-specific screens. Recently, a
Marquis Fleishman
July 27, 2023