Marquis Fleishman

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Generation of a human haploid neural stem cell line for genome-wide genetic screening

Characterization of the pluripotency and haploidy of extended pluripotent human haploid embryonic stem cells. Credit: World Journal of Stem Cells (2023). DOI: 10.4252/wjsc.v15.i7.734 Haploid embryonic stem cells (haESCs) have been established in many species. Differentiated haploid cell line types in mammals are lacking due to spontaneous diploidization during differentiation that compromises lineage-specific screens. Recently, a

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